BDNF Val66Met polymorphism and protein levels in Amniotic Fluid
نویسندگان
چکیده
منابع مشابه
Cognition, serum BDNF levels, and BDNF Val66Met polymorphism in type 2 diabetes patients and healthy controls
Background and aims Type 2 diabetes (T2DM) is associated with cognitive deficits. However, their pathophysiological mechanisms are still unknown. Recent study suggests that brain-derived neurotrophic factor (BDNF) is correlated with cognitive deficits in T2DM patients. This study was to determine whether altered serum BDNF levels and cognitive deficits depended on the BDNF Val66Met polymorphism...
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335 BDNF Genotype and Sleep Intensity—Bachmann et al Moreover, in adult rats, the degree of exploratory behavior predicts the level of BDNF as well as of SWA during subsequent sleep.10 Finally, pharmacological experiments such as injections of exogenous BDNF, an anti-BDNF antibody, and an inhibitor of tyrosine kinase B receptor, the high-affinity BDNF receptor, consistently suggest that this re...
متن کاملAssociation between the BDNF Val66Met Polymorphism and Chronicity of Depression
OBJECTIVE Both clinical and biological factors influence the course of depressive disorders. This study tested for associations between the brain-derived neurotrophic factor (BDNF) gene at the Val66Met locus and the course of major depressive disorder (MDD). METHODS Three hundred ten Korean subjects (209 patients, 101 controls) were genotyped for rs6265 at nucleotide 196 (G/A), which produces...
متن کاملBDNF Val66Met polymorphism alters sympathovagal balance in healthy subjects.
A common polymorphism of the brain-derived neurotrophic factor (BDNF) gene (Val66Met) has been implicated in anxiety, which is associated with lower vagal activity. We hypothesize that the BDNF Val66Met polymorphism may have a modulatory effect on the cardiac sympathovagal balance. A total of 211 healthy Chinese-Han adults (58 male, 153 female, aged 33.3 +/- 10.3 years) were recruited with thre...
متن کاملA BDNF Val66Met Polymorphism and Ketamine-induced Rapid Antidepressant Action
TO THE EDITOR Accumulating evidence suggests that brain-derived neurotrophic factor (BDNF) plays a key role in the patho-physiology of major depression, as well as the therapeutic action of antidepressants. 1,2) Serum levels of BDNF in drug naïve patients with major depression are significantly lower than those in normal controls. Additionally, serum levels of BDNF in drug naïve patients can be...
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ژورنال
عنوان ژورنال: BMC Neuroscience
سال: 2010
ISSN: 1471-2202
DOI: 10.1186/1471-2202-11-16